Introduction: It has been known for more than a century that there are nerve endings in various organs and tissues comprising the immune system (1). The mechanisms by which neuroendocrine agents can act as messengers within the immune system, and immunological cell products can participate in the control of the CNS functions have been described in the scientific literature (2). Anecdotal and scientific evidence have been shared by doctors and students of chiropractic, and patients, concerning improved health status, in addition to resolution of musculoskeletal complaints, from receiving chiropractic care (3,4). In 1993, Allen conducted a review of the literature to determine whether there was scientific evidence on the effects of chiropractic on the immune system (5).